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Irinotecan (eye-rin-oh-tee-kan) (also known as Camptosar, CPT-11, irinotecan hydrochloride) is a chemotherapy drug used to treat colon or rectal cancer. It may also be used for other cancers.
With respect to colon or rectal cancer that has spread beyond the colorectum (metasticized), Irinotecan is used in combination with 5-FU and Leucovorin both before and after surgery. The combination is referred to as FOLFIRI. (For information about FOLFIRI, cilck here).