Content Overview 
- Summary
- Why Chemotherapy Drugs Can Cause Nausea and Vomiting
- Definition of Nausea, Retching, Vomiting, Anticipatory Vomiting
- Drugs Which Are More Likely To Cause Nausea And Vomiting
- Factors Which Are More Likely To Cause Nausea And Vomiting
- Methods For Preventing Anticipatory Vomiting
- Non-Drug Methods For Preventing Or Reducing Nausea and Vomiting
- Drugs Which Can Be Used To Prevent Nausea And Vomiting
- What To Do And No Do If You Just Had A Bout Of Vomiting
- A Bag To Carry "Just In Case"
- Foods and Drinks That May Be Easier On The System
- Foods To Avoid When Feeling Nauseous
Chemotherapy Side Effects: Nausea and Vomiting
Why Chemotherapy Drugs Can Cause Nausea and Vomiting
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© American Cancer Society 2010
Chemotherapy drugs cause nausea and vomiting for a variety of reasons.
- One reason is they irritate the lining of the stomach and duodenum (the first section of the small intestine). This stimulates certain nerves that activate the vomiting center (VC) and the chemoreceptor trigger zone (CTZ) in the brain which leads to vomiting.
- Another way these areas of the brain can be activated is through obstruction (intestinal blockage), delayed gastric emptying, or inflammation -- all possible effects of chemotherapy.
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