The Different Types of Chemotherapy Drugs
Mitotic Inhibitors
Next » « Previous7/8
This content was provided by
© American Cancer Society 2010
Mitotic inhibitors are often plant alkaloids and other compounds derived from natural products. They can stop mitosis or inhibit enzymes from making proteins needed for cell reproduction. These work during the M phase of the cell cycle but can damage cells in all phases. They are used to treat many different types of cancer including breast, lung, myelomas, lymphomas, and leukemias. These drugs are known for their potential to cause peripheral nerve damage, which can be a dose-limiting side effect.
Examples of mitotic inhibitors include:
- the taxanes: paclitaxel (Taxol ®), docetaxel (Taxotere ®)
- epothilones: ixabepilone (Ixempra ®)
- the vinca alkaloids: vinblastine (Velban ®), vincristine (Oncovin ®), and vinorelbine (Navelbine ®)
- estramustine (Emcyt ®)
Get Your Personal Guide
Please share how this information is useful to you. 0 Comments
Post a Comment Have something to add to this topic? Contact Us.