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Most insurers pay for medical costs relating to clinical trials the subject of which is treatment, early-detection or diagnosis. Prevention trials are generally not covered.

Several states, including Maryland and Rhode Island, mandate that health insurance coverage extend to clinical trials for people with a life threatening condition.

To improve the chances of your insurer paying for the costs, take the following steps which are based on recommendations of the National Institutes of Health:

Step 1. Understand the costs associated with the trial.
Step 2. Ask about the experience of other patients in the trial.
Step 3. Understand the provisions of your health plan.
Step 4. Enlist the help of a source of influence.
Step 5. Coordinate the request to the insurer with your doctor and the administrator of the clinical trial.
Step 6. If the insurer's decision will be the deciding factor about whether you will join the trial, set a deadline to answer.

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