Content Overview
- Overview
- Life During a Continuous FOLFOX Infusion: Do's and Don'ts
- FOLFOX and Work
- Paying For FOLFOX Treatment
- FOLFOX: How Treatment Is Delivered (Infusion, Continuous Infusion)
- FOLFOX and Food
- How Chemotherapy Works
- Ports: Defined, Advantages, Risks, Care Of
- FOLFOX Variations
- FOLFOX Side Effects: What They Are And How To Cope With Them
- The Drugs Which Make Up FOLFOX
- How To Prepare For FOLFOX Infusions
- Implanting A Port
- What Happens During a Continuous FOLFOX Infusion
- What Happens During FOLFOX Infusion At The Treatment Center
- What NOT To Do While On FOLFOX Treatment
- Red Flags to Watch For While Undergoing FOLFOX Treatment
- Living With A Port When Not Being Infused
- Removal of A Port
- Nearing The End Of FOLFOX Treatment
- Recovery From FOLFOX Treatment
- Life After FOLFOX Treatment: Long Term
- Your Health Care Team
- Emotions And Feelings While Undergoing FOLFOX Treatment
- Disability Income From SSDI and/or SSI Or A Private Insurer
- FOLFOX and Sex
- If You Have Advanced Colorectal Cancer
- If Treatment Is Not Working
- FOLFOX Family and Friends
Chemotherapy: FOLFOX
The Drugs Which Make Up FOLFOX
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FOLFOX is a combination of two chemotherapies and a helper drug:
- “FOL” comes from Folonic Acid, better known as Leucovorin (leu-co-voor-in). Leucovorin is the helper drug. It is a vitamin-like drug which makes another ingredient, 5-FU, more effective by making the effect on the cells longer lasting, usually without worsening the side effects of the other drugs. When Leucovorin is not available, Fusilev is often used as a substitute.
- “F” represents Flourouracil, commonly referred to as 5-FU (five-flure-oh-YOOR-a-sill). 5-FU is a chemotherapy from the 1950’s which is only effective in the body for a short period of time, somewhere between 30 and 60 minutes. Because it is short acting, 5-FU is administered over a long period of time either by infusion when it is commonly referred to as 5-FU, or in pill form which turns into 5-FU when it makes contact with a tumor . The pill form is known as Capecitabine (Xeloda)],
- "OX” represents Oxaliplatin. (ox-AL-i-PLA-tin) – a relatively new chemotherapy that is very effective against colorectal cancer cells
FOLFOX is usually administered together with:
- A steroid to help prevent nausea and vomiting, to reduce swelling, and sometimes to increase appetite,
- Another anti-nausea medication.
FOLFOX is administered in several different variations. The variations are described in the section below. The main difference between the variations is the doses of the three drugs and the ways they are given.
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