Content Overview 
- Overview
- Life During a Continuous FOLFOX Infusion: Do's and Don'ts
- FOLFOX and Work
- Paying For FOLFOX Treatment
- FOLFOX: How Treatment Is Delivered (Infusion, Continuous Infusion)
- FOLFOX and Food
- How Chemotherapy Works
- Ports: Defined, Advantages, Risks, Care Of
- FOLFOX Variations
- FOLFOX Side Effects: What They Are And How To Cope With Them
- The Drugs Which Make Up FOLFOX
- How To Prepare For FOLFOX Infusions
- Implanting A Port
- What Happens During a Continuous FOLFOX Infusion
- What Happens During FOLFOX Infusion At The Treatment Center
- What NOT To Do While On FOLFOX Treatment
- Red Flags to Watch For While Undergoing FOLFOX Treatment
- Living With A Port When Not Being Infused
- Removal of A Port
- Nearing The End Of FOLFOX Treatment
- Recovery From FOLFOX Treatment
- Life After FOLFOX Treatment: Long Term
- Your Health Care Team
- Emotions And Feelings While Undergoing FOLFOX Treatment
- Disability Income From SSDI and/or SSI Or A Private Insurer
- FOLFOX and Sex
- If You Have Advanced Colorectal Cancer
- If Treatment Is Not Working
- FOLFOX Family and Friends
Chemotherapy: FOLFOX
FOLFOX Variations
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The three FOLFOX variations in common usage are FOLFOX 4, FOLFOX 6 and FOLFOX 7.
FOLFOX 4, 6 and 7 vary the Oxaliplatin dose and other aspects of delivery. Two of the objectives of the variations are to reduce side effects and to improve effectiveness.
FOLFOX4
- Day 1: in the treatment center:
- Infusion of Oxiliplatin and Leucovorin plus a steroid, an anti-nausea medication and possibly other meds aimed at reducing side effects. If you will also receive Avastin, it will be included in the infusion. (Avastin is intended to slow the growth and spread of tumors by stopping the formation of blood vessels that bring oxygen and nutrients to tumors.)
- 5 minute injection of 5-FU
- Attachment of an ambulatory infusing device containing a 22 hour supply of 5-FU to a port which was previously implanted under the skin. (An ambulatory device is a container that goes with you as you move around.)
- You go home with the infusing device.
- Day 2: Swap the 22 hour supply for another 22 hour supply of 5-FU. The swap either happens at the treatment center or a home nurse comes to you.
- Day 3: 22 hours later: The pump is removed -- either at the treatment center or a home nurse comes to you.
FOLFOX6 and FOLFOX 7
- Day 1: in the treatment center:
- Infusion of Oxiliplatin and Leucovorin plus a steroid, an anti-nausea medication and possibly other meds aimed at reducing side effects. The amount of Oxiliplatin and Leucovorin varies between FOLFOX6 and FOLFOX7.
- If you will also receive Avastin, it will be included in the infusion. (Avastin is intended to slow the growth and spread of tumors by stopping the formation of blood vessels that bring oxygen and nutrients to tumors.)
- 5 minute injection of 5-FU
- Attachment of an ambulatory infusing device to your port of a 46 hour supply of 5-FU.
- You go home with the infusing device.
- Day 2: 46 hours later: the pump is removed either at the treatment center or a home nurse comes to you.
NOTE: If you medical care at home, home health care is available. For information, including how to choose an agency, click here.
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