Chemotherapy For Specific Areas Of The Body (Regional Chemotherapy)
Intra-Arterial Infusions
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Intra-arterial infusions gained some popularity during the 1980s.
An intra-arterial infusion allows a chemotherapy drug to be given directly to the tumor through a catheter placed in the artery that supplies blood to the tumor. This method is used to treat disease in an organ such as the liver (isolated hepatic perfusion) or to treat an extremity such as the leg (isolated limb perfusion). The goal is to concentrate the drug in the areas of the tumor and decrease systemic effects.
The catheter is attached to an implanted or portable pump.
Although this approach sounds like a good idea for better effectiveness and fewer side effects, most studies have not found it to be as useful as was expected. This approach is still being studied in clinical trials. Except for these studies, it is rarely available outside of specialized cancer centers.
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